HEALTH STUDY: Researchers at Vanderbilt-Ingram Cancer Center in America made a big effort to strengthen the discovery of genes Transcriptomic-wide association study (TWAS) did and for Splicing-called TWAS An alternative view was put forward.
TWAS A genetic method that can be used to compare the genetic components of a trait and the genetic components of a trait to determine whether a relationship exists between the two components.
The study, published in the Journal of the US National Cancer Institute, found oncogenic roles for two previously unreported genes, TRPSI and METRNL, and confirmed an association with cancer risk with another recently reported gene, C14ORFL66. .
Senior author Xingyi Guo, associate professor of medicine and biomedical informatics, said in the study they used new large RNA-seq data and employed the TWAS approach along with splicing-TWAS to enhance novel gene discovery.